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            <title>Insights on the Depression and Anxiety</title>
            <link>https://www.depanxietyjournal.com/feed</link>
            <description>Introduction
Depression is a condition in which a person feels discouraged, sad, hopeless, unmotivated or disinterested in life. Depression and Anxiety disorders are different; however people with depression often experience symptoms of an anxiety disorder, such as nervousness and irritability problems. Over the past few years, researchers have been moving towards a conclusion that depression and anxiety are two faces of one disorder. Research surveys show that 70% of people undergoing depression also have anxiety and most mood disorders represent a combination of anxiety and depression.
Insights on the Depression and Anxiety is a research journal publishing methodically peer&#45;reviewed manuscripts to disseminate insights on the factors that influence the development and the long&#45;term prognosis of anxiety and depression.
Insights on the Depression and Anxiety exerts a motive to publish manuscripts that can assist in improvement of appropriate preventative measures and care for persons with anxiety or depression.
Reasons for Publishing
Depression and Anxiety disorders are common at all ages. The shared cornerstone of anxiety and depression is the perceptual process of overestimating the risk in a situation and underestimating personal resources for coping. Further, anxiety and depression share an avoidant coping style. Sufferers avoid what they fear instead of developing the skills to handle the kinds of situations that make them uncomfortable.
Therefore, Insights on the Depression and Anxiety initiated publishing manuscripts focusing on different disguised aspects that make people susceptible to anxiety disorders or depressions.
Insights on the Depression and Anxiety also seeks to project the influence of biological and genetic factors on anxiety and depression disorders; and the implications of a depression or anxiety on an Individual work&#45;life balance.</description>

                    <item>
            <type>Research Article</type>
            <title>Screening for Depressive Symptoms in Clinical and Nonclinical Youth: The Psychometric Properties of the Dutch Children’s Depression Inventory&#45;2 (CDI&#45;2)</title>
            <author>Denise HM Bodden,Yvonne Stikkelbroek,Daan Creemers,Sanne PA Rasing,Elien De Caluwe,Caroline Braet</author>
            <pubDate>2025-12-24 00:00:00</pubDate>
            <description>Objective: This study investigated the utility of the second version of the Children&amp;rsquo;s Depression Inventory (CDI-2) as a screening tool to identify children and adolescents aged 8-21 years suffering from depressive symptoms.&amp;nbsp;Method: Data were collected by combining questionnaire data from multiple clinical and control subsamples in which the CDI-2 child and parent version were administered to clinically depressed children (n = 111), children with other psychiatric disorders (n = 74) and control children (n = 2246) as well as their parents (respectively n = 104, n = 112, n = 2130).&amp;nbsp;Results: Results showed that the CDI-2 has good psychometric properties in terms of internal consistency, factor structure, parent-child agreement, convergent and divergent validity. However, the factor structure of the parent version was insufficient. The CDI-2 total score of the child version and parent version can differentiate between clinically depressed children, children with other psychiatric disorders, and control children. Further, reliable cut-off scores were established. There were also significant gender and age effects.Conclusion: The total score of the CDI-2 child and parent version can be used as a screening tool to detect clinically significant depressive symptoms in children and adolescents.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1047.pdf</link>
        </item> 
                    <item>
            <type>Short Communication</type>
            <title>Optimizing Treatment of Depression, Trauma, and Anxiety Disorders through Neurophysiological Interventions</title>
            <author>Kees Blasé</author>
            <pubDate>2025-10-15 15:38:36</pubDate>
            <description>Depression, trauma, and anxiety disorders continue to be predominant causes of global disability, with typical therapies proving to be only marginally successful. Heart Rate Variability Biofeedback (HRVB) offers patients a self-regulation method that improves the flexibility of the autonomic nerve system via resonance breathing. Clinical research shows that training can significantly lower symptoms of sadness and PTSD, with improvements shown after 4 to 8 weeks. HRVB is inexpensive, non-invasive, and scalable, making it a promising supplementary therapy in psychiatry. Subsequent study ought to inform its incorporation into clinical protocols.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1046.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Investigating the Effect of the Family&#45;Centered Empowerment Model (FCEM) on the Empowerment Indicators of Student Girls with Iron Deficiency Anemia (IDA) and Their Mothers</title>
            <author>Fatemeh Alhani,Hasan Navipor,Fatemeh Sadat Seyed Nematollah Roshan</author>
            <pubDate>2025-08-27 11:57:30</pubDate>
            <description>Background and aims: Iron deficiency is one of the most important health issues in adolescents, especially girls. Today, empowerment is considered an effective program to change behavior in chronic disease control. This study was conducted to determine the effect of the family-centered empowerment model on the empowerment indicators of student girls with iron deficiency anemia and their mothers.Methods: This is a two-group semi-experimental study conducted on 60 student girls along with their mothers, who were selected by a two-stage cluster random sampling method. Data was collected using a demographic information questionnaire and an adolescent and mother empowerment questionnaire. The intervention based on the family-centered empowerment model was implemented for the test group, and after 1.5 months, data from both groups were collected and analyzed with chi-square, independent t, and paired t-tests.Results: The results of the independent t-test showed that there was a significant difference between the student girls in the test and control groups after the intervention in terms of empowerment indicators (p &amp;lt; 0.05). The results of the independent t-test showed that there was a significant difference between the mothers in the test and control groups after the intervention in terms of ability indicators (p &amp;lt; 0.05), while before the intervention, this difference was not significant (p &amp;gt; 0.05).&amp;nbsp;Conclusion: The results of the present study showed that the implementation of the family-centered empowerment model not only increased the empowerment indicators of student girls with iron deficiency anemia but also had an effect on the empowerment of their mothers.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1045.pdf</link>
        </item> 
                    <item>
            <type>Mini Review</type>
            <title>Climate Change and the Untold Story of Ecoanxiety</title>
            <author>Manar Zaki</author>
            <pubDate>2025-07-24 09:54:22</pubDate>
            <description>Anthropogenic activity has escalated the planet&amp;rsquo;s temperature and resulted in dire consequences on our environment, and our health, whether physical or mental. The imbalance created in the planet&amp;rsquo;s environmental conditions has consequently caused a rupture in mental health, and ecoanxiety has become one of the adverse indirect repercussions. Not quite recently, a sense of urgency has been spreading in the literature of climate change, evoking a call for action, and requesting commitment from us all: individuals, communities, and countries. This paper attempts to establish a link between the climate crisis and ecoanxiety in the aim to restore our cognition of our roles to save the planet, salvage our health and preserve, and conserve, environmental resources for future generations.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1044.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Return to Driving in Mild Traumatic Brain Injury: Evaluation of Coping Strategies, Resilience, and Psychological Distress</title>
            <author>Tisha J Ornstein,Erica S Cuevas,Maire L O’Hagan,Samantha R Pejic</author>
            <pubDate>2025-07-03 14:17:53</pubDate>
            <description>Background: This study explored whether emotional distress, coping, and/or resilience contributed to return to driving (RTD) following experienced mild traumatic brain injury, and whether these variables of interest differed among those who had and had not RTD. &amp;nbsp;Methods: The present study evaluated de-identified archival data of 65 patients with mTBI following an MVA. Patients were either the driver, passenger, /or pedestrian struck by a motor vehicle, and aged 22 to 69 years. The sample consisted of 36 men and 29 women with an average education. The mean months elapsed between the accident and the assessment was 16.82 months. Pearson correlations were used to test for associations between all explanatory and outcome variables. Separate linear and hierarchical regressions were carried out to evaluate whether variables of interest were significant predictors of RTD. &amp;nbsp;Results: Findings revealed that the presence of depressive symptoms was associated with coping, irrespective of style, resilience, driving-related anxiety, and RTD. Moreover, RTD was related to driving-related anxiety, too, and in fact, anxiety (considering the presence of depressive symptoms) appeared to be an even greater limiting factor when considering RTD in this population. Age, gender, and education did not influence RTD.&amp;nbsp;Conclusion: The present study revealed that depressive symptoms and driving-related anxiety in particular contribute to whether patients with mTBI RTD, irrespective of time since injury, age, and gender. Coping styles and resilience did not predict RTD. Further work is warranted to address the paucity of research investigating RTD parameters that contribute to and/or hinder RTD among mTBI sufferers.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1043.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>The Primary Care Treatment System for Severe Depression: Perspectives of Patients, Doctors, Treatment Guidelines and Treatment System Failures</title>
            <author>Tony Frais MA*</author>
            <pubDate>2024-06-13 10:56:40</pubDate>
            <description>There are a number of key issues that matter to patients and General Physicians (GPs) in the primary care treatment system for severe depression. Patient and doctor narratives can contribute by highlighting these key issues. Various systems are employed in treating severe depression. However, there needs to be an investigation using systems failure methodology and how this methodology is applied which can help identify how and why the NHS treatment system for severe depression can fail patients in terms of provision of effective care.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1042.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Alcohol and Substance Abuse in the General Population during the COVID&#45;19 Pandemic: Results of the COMET&#45;G International Study</title>
            <author>Elias Tzavellas*, Vasilopoulos Efthimios, Panagiota Bompori, Seri Abraham, Kristina Adorjan</author>
            <pubDate>2024-04-15 15:19:54</pubDate>
            <description>The global impact of the COVID-19 pandemic on mental health and substance use behaviors has sparked extensive research efforts. The COMET-G international study, organized by the Department of Medicine and the Rectorate of the Aristotle University of Thessaloniki in collaboration with the World Psychiatric Association, delved into these issues. Running from March 2020 to April 2021, the study collected responses from 55,589 individuals across 40 countries. Through a comprehensive questionnaire, participants provided insights into their mental state, attitudes toward the pandemic, and the resultant changes in their personal and daily lives. Findings revealed, among other things, significant patterns of change in substance use, with notable correlations between reduced usage and the severity of lockdown measures among non-binary individuals. Mental health history emerged as a strong predictor of substance use changes, with influences from anxiety disorders, depression, and self-harm. Additionally, family and social dynamics, including economic expectations and household composition, significantly shaped substance use behaviors during lockdowns. Given these findings, the development of comprehensive approaches targeting the adverse effects of the pandemic on individual behaviors and general welfare is crucial.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1041.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Death Wishes, Aging Patients, and Euthanasia</title>
            <author>Mareike Wolf-Fédida, Jelena Rosic, Gilles Arsène Aizan, Fanny Houzé, Laurent Vidal</author>
            <pubDate>2024-03-12 16:17:48</pubDate>
            <description>The authors are searchers in psychopathology and communicate here about the dead wishes in relation to euthanasia. In Europe, the question comes regularly up to know if the law should be changed concerning the prohibition of euthanasia. The health system obeys progressively a modern idea of comfort and the &amp;ldquo;good life&amp;rdquo;. The authors are psychotherapists and their methodology is based mainly on phenomenological psychology, psychoanalysis, and psychopathology. Statistics of the French Ministry of Health will support their statements. Different clinical experiences with young patients, aging patients, or near-to-death patients are crossed and compared to those marked by heavy experiences like rape or amputation. The unbearable nature of their suffering makes them ask frequently to stop the pain. They would prefer being dead. This contribution examinates this kind of demand to find a helpful position for the caregiver and the patient. We should consider that near-death patients may often be at the climax of anxiety and depression is likely to switch over to dementia. In asking to finish with life, this purpose may change one day to another &amp;ndash; sometimes it just highlights the wish to see things changed. The position of society and the medical staff has a high influence as well. Asking for euthanasia shows the variety of the same words that have different meanings from a medical, psychological, or psychopathological viewpoint. The purpose is to consider these aspects with the patient&amp;rsquo;s demand.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1040.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Systemic Lupus Erythematosus and Depression Overview</title>
            <author>Ahmed Shaaban,Nourelhouda Said,Hoda Afifi</author>
            <pubDate>2024-01-03 15:06:01</pubDate>
            <description>Systemic lupus erythematosus (SLE) is a chronic inflammatory multisystem disorder that commonly affects females during their reproductive years. It is characterized by the presence of autoantibodies and immune complex deposition, the etiology is not known but the interaction of an environmental agent in a genetically susceptible individual is thought to be fundamental. SLE most frequently involves the skin, joints, lungs, heart, kidney, and neuropsychiatric manifestations that may occur during the course of the disease. Mood disorders among SLE patients, particularly depression, are common and important psychiatric manifestations of the disease, in addition to their high incidence and possible deleterious influence on disease progression, so early identification and treatment of depression may have a significant influence on the patient&amp;rsquo;s quality of life.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1039.pdf</link>
        </item> 
                    <item>
            <type>Commentary</type>
            <title>The Ramifications of Loneliness:  A Commentary</title>
            <author>Ami Rokach*</author>
            <pubDate>2023-09-08 17:07:49</pubDate>
            <description>Loneliness was a major concern of people during the recent COVID-19 pandemic. Now, that the pandemic is mainly gone, it is still a global issue. This commentary reviews the impact on that loneliness has on our cognitive, behavioral and affective functioning. These effects are described, along with the stigma that often accompanies loneliness and which makes it hard for people to acknowledge and admit that they are lonely, and seek help from healthcare professionals. This commentary, aside from describing the various negative implications of loneliness, highlights the need for society to address the issue. While it cannot be eliminated, the population can be taught how to recognize it, and how to offer assistance to those who struggle with it.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1038.pdf</link>
        </item> 
                    <item>
            <type>Short Communication</type>
            <title>Sustainable Development Work Aimed at Promoting Mental Health among Municipal Adult Students with Mental Health Problems</title>
            <author>Ulla Damber*, Lena Randevåg</author>
            <pubDate>2023-08-07 16:31:23</pubDate>
            <description>The present study focuses on students and teachers in Swedish Municipal Adult Education, in a project aimed at helping students with diagnoses within the neuropsychiatric spectrum. The project aimed to support students to complete their studies for further higher education. As this is an overlooked group of students research results provide insights into students&amp;rsquo; views on the project and conclusions regarding the sustainability of school development. In this qualitative study, five teachers and four teachers were observed and in-depth interviewed. Data were analyzed through inductive content analysis. Authentic relations between students and teachers, signified by mutual trust, proved important. As the teachers themselves had originated the ideas guiding the project, the development work had good prior conditions for further sustainable development. &amp;nbsp;We conclude that autonomous teachers, who set up joint goals and provide individualized support for these students, enable academic success when flexibility, relations, and self-esteem characterize the work.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1037.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Betty Neuman System Model: A Concept Analysis</title>
            <author>Adnan Yaqoob*, Rafat Jan, Salma Rattani and Santosh Kumar</author>
            <pubDate>2023-08-04 16:26:43</pubDate>
            <description>Introduction: Nursing theories are critical as they drive nursing education, practice, and research. Neuman Systems Model (NSM) considers a person a complete system with integrated psychological, physiological, spiritual, social, and developmental components. Nurses give their patients physical, emotional, and psychological assistance and are subjected to mental and physical pressure due to these responsibilities, impacting their health, psychological well-being, and interpersonal relationships. This paper aims to perform a concept analysis of stressors proposed in NSM about lines of defense and the level of preventive interventions that can affect a person&amp;rsquo;s well-being. Further, this paper discusses knowledge generation through NSM&amp;rsquo;s applicability to preventing exhaustion and burnout among nurses.&amp;nbsp;Methodology: This theoretical attempt is carried out using the theory analysis approach suggested by Walker and Avant (2019).Discussion: Nursing is a career that requires a great deal of dedication and personal engagement. Nurses are subjected to recurrent stresses due to technological advances and rising demands. Burnout occurs when nurses get discouraged and have less compassion for the patients due to recurrent burdens. Stress and burnout are two of the most common reasons for nurses to quit hospitals. The NSM is concerned with stresses that may affect a person&amp;rsquo;s health and well-being (prediction). Nurses assist patients at the most vulnerable and challenging times, such as surgical procedures, traumas and personal and physical losses.Conclusion: The NSM enables the investigation of preventative and protective treatments. Because of the model&amp;rsquo;s flexibility, it may be used in a wide range of nursing situations. Administrative, hospitals, clinics, and other nurses can benefit from this paradigm. Evaluating the many distinct elements contributing to burnout is also feasible. The model&amp;rsquo;s client factors of physiological, sociocultural, developmental, and spiritual characteristics are used to achieve this. Viewing the individual as an open system that responds to environmental stimuli encourages the existence of stressors that might lead to burnout.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1036.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Is binge watching among medical students associated with depression and anxiety?</title>
            <author>Meriem Hamza,Soumeyya Halayem,Imène Jraidi,Myriam Boudali,Asma Bouden,Ahlem Belhadj</author>
            <pubDate>2023-03-21 14:39:20</pubDate>
            <description>Objectives: Investigate binge-watching (BW) behavior among students and assess its correlation with anxiety and depressive symptoms.&amp;nbsp;Methods: Medical students who met the definition of BW were divided, according to their viewing frequency, into three groups: G1: once a month or less, G2: once a week or once every two weeks, and G3: twice a week or more. Beck Depression Inventory and State-Trait Anxiety Inventory were used.&amp;nbsp;Results: Ninety-four participants were recruited. The prevalence of BW was 72.3%. Depression and anxiety scores didn&amp;rsquo;t differ between binge watchers and the non-binge watcher group. G2 was found to be significantly less depressed (p = 0.014) and had a lower anxiety state (p = 0.05) and anxiety trait scores (p = 0.026) than the control group. Feeling tired was the most prevalent reason to stop viewing among G3 (p = 0.001).&amp;nbsp;Conclusion: Binge-watching could be when used in a specific manner, a way to cope with negative feelings.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1035.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Clinical and immunological characteristics of depressive patients with a clinical high risk of schizophrenia</title>
            <author>Omelchenko MA,Zozulya SA,Kaleda VG,Klyushnik TP</author>
            <pubDate>2023-03-03 11:37:02</pubDate>
            <description>Objective: To study clinical and immunological characteristics of depressive patients with high clinical risk of schizophrenia.Materials and methods: We examined 30 depressive patients with attenuated positive symptoms (APS), which indicates a clinically high risk of schizophrenia, 20 depressive patients without APS and 27 healthy volunteers with no mental disorders. APS identified according to the presence of three or more scores on at least one of the following items on the Scale of Prodromal Symptoms (SOPS) positive symptoms subscale: P1 (Unusual thought content/Delusional ideas), P2 (Suspiciousness/Persecutory ideas) and P4 (Perceptual abnormalities/Hallucinations). The psychometric assessment was carried out on the Hamilton Depression Rating Scale (HDRS), SOPS, and the Scale for Assessment of Negative Symptoms (SANS). The activity of leukocyte elastase (LE) and &amp;alpha;1-proteinase inhibitor (&amp;alpha;1-PI), the autoantibodies to neoantigens S100B and myelin basic protein, and the ratio of LE and &amp;alpha;1-PI activity or Leukocyte Inhibitory Index (LII) were determined.&amp;nbsp;Results: The activity of inflammatory markers LE and &amp;alpha;1-PI was increased in patients in both clinical groups compared with controls. In the total group of patients, the associations between LII and the score on the positive subscale SOPS, and between LII and the score on the negative subscale SOPS and SANS scale with the most pronounced association with the SANS subscales &amp;laquo;Affective Flattening or Blunting&amp;raquo; and &amp;laquo;Alogia&amp;raquo; were established.&amp;nbsp;Conclusion: The identified correlations between immune response features and positive and negative symptoms in depressive patients may have prognostic value for establishing a high risk of schizophrenia.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1034.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Identifying mothers experiencing emotional distress in the neonatal intensive care unit. Application of PPTSD questionnaire in a Greek NICU population</title>
            <author>Karkani Anastasia,Theodoraki Martha,Paraskeva Natasa,Kouros Pavlos Aristidis,Pantelis Perdikaris,Rosenblum Ouriel,Mazet Philippe</author>
            <pubDate>2022-10-07 17:25:27</pubDate>
            <description>The birth of a high-risk infant such as an extremely premature infant can represent an important traumatic experience for mothers. Perinatal Post Traumatic Stress Disorder Questionnaire (PPTSDQ) explores retrospectively maternal post-traumatic stress reaction. This shelf-rating questionnaire explores the potential for experiencing posttraumatic symptoms related to childbirth and the ensuing post-natal period. The PTSD questionnaire was originally developed by DeMier and Hynan and their colleagues at the University of Wisconsin and has been widely used in research and in clinical practice for identifying mothers experiencing significant emotional distress during the post-natal period, so they may be referred for mental health services. The present study aims to introduce this tool in perinatal settings as an early intervention. It has been widely used with other measures of post-traumatic stress and depression, such as the Openness Scale from the NEO-PR, the self-report measure of depression BDI-II, the IES (Impact Event Scale) and the EPDS (Edinburgh Postnatal Depression Scale).&amp;nbsp;Although already a useful clinical instrument the current study used the revised version. This modification refines the response options from dichotomous choices to a Likert scale format by Callahan Borja and Hynan.&amp;nbsp;Numerous qualitative and quantitative studies state that premature delivery is a highly stressful event and document the full range of post-traumatic sequelae, such as intrusive recollections, behavioral avoidance, and hyperarousal, as well as attachment difficulties following childbirth. Furthermore, the severity of neonatal complications and gestational age have been found to be predictive of PTSD symptomatology in parents as measured by the PPQ. For this reason, the current study aims to give increased focus to mothers having a premature birth and often expecting their children to die. The sample comprises 25 mothers of prematurely born infants hospitalized in the NICU and 25 mothers of full-term infants born in the maternity ward of the same Greek hospital who responded to the Perinatal PTSD Questionnaire and equally the PERI a postnatal complication rating inventory and the clinical interview for parents CLIP.Mothers of high-risk infants present post-traumatic stress reactions related to prematurity. The Perinatal PTSD Questionnaire identifies postnatal maternal distress but should not substitute a clinical interview, yet findings indicate that equally identifies pre-existing distress symptoms associated with maternal personality traits that emerged with the traumatic event of the unexpected birth.Due to the consistency of the population of the experimental group, who come mostly from the provinces, the possibility of a follow- up of the cases is quite limited.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1033.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Effectiveness of structured teaching programme on knowledge regarding management of extravasation of chemotherapeutic drugs</title>
            <author>Pooja Prakash,Ayush Chandra,Malathi Kotha,Santosh Kumar Das,Barsha Prakash,Avinash Chandra,Gyaljin Sherpa,Sudikshya Acharya</author>
            <pubDate>2022-09-13 10:40:36</pubDate>
            <description>Background: More than 1 million intravenous chemotherapy infusions are given worldwide each day which leads to extravasation. Health professionals must know the drugs that cause tissue injury and take the necessary measures to prevent extravasation.Objectives: The study aimed to assess the knowledge regarding the management of extravasation of chemotherapeutic drugs before and after the implementation of a structured teaching program among staff nurses.Method: The pre-experimental group pre-test and post-test designs were adopted for the study. The convenience sampling technique was used to obtain 30 staff nurses of Ramaiah Medical College Hospital, India. Both Pre-test and Post-test were performed using the same structured knowledge questionnaire followed by 45 minutes of the structured teaching program. Data were processed through Statistical Package for Social Sciences version 20 and analyzed using descriptive and inferential statistics.Results: More than half of the subjects were female (66.7%) and 36.7% of the subject had more than 10 years of professional experience. Most of the subjects (70%) had inadequate knowledge during the pretest. The mean knowledge score was 15.33 &amp;plusmn; 4.003 and 24.67 &amp;plusmn; 5.384 in pre-test and post-test respectively. There was a significant difference in pre-test and post-test knowledge scores regarding the management of extravasation of chemotherapeutic drugs.&amp;nbsp;Conclusion: The Study concluded that the structured teaching program was significantly effective in improving the knowledge regarding the management of extravasation of chemotherapeutic drugs among nurses.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1032.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Predicting physical symptoms through expressions of loneliness and anxiety in individuals utilizing social media during SARS&#45;CoV&#45;2</title>
            <author>Vasiliki Georgoulas-Sherry</author>
            <pubDate>2022-04-25 15:33:38</pubDate>
            <description>The effect of the novel coronavirus (SARS-CoV-2) pandemic has produced significant health concerns negatively impacting individuals. As the ongoing and constantly changing nature of SARS-CoV-2 continues, the unique characteristics of this pandemic trend toward anxiety and loneliness as significant behavioral health outcomes. Furthermore, the SARS-CoV-2 pandemic has significantly impacted the utilization of social media platforms such as Twitter. Utilizing over 1.6 million tweets from approximately 988,760 Twitter users geolocated in Washington state from the University of Pennsylvania&amp;rsquo;s publicly available Twitter database (from March 2020 to March 2021), this study evaluated the impact of SARS-CoV-2 by using expressions of loneliness and anxiety to predict mental and physical symptoms. Bivariate correlations revealed expressions of loneliness were correlated to trouble breathing while expressions of anxiety were correlated to skin lesions, body aches, flu-like, seasonal cold, trouble breathing, nausea or diarrhea, fever, chills, and cough. Multiple multivariate linear regressions were completed, and a significant regression equation was found in predicting trouble breathing symptoms on expressions of loneliness and anxiety, however, the proportion of variance was 8% of the observed variation in the model. Further implications revealed the importance of understanding mental and physical well-being during a public health crisis as well as the use of social media platforms as primary and supplementary stimuli.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1031.pdf</link>
        </item> 
                    <item>
            <type>Mini Review</type>
            <title>Stage and symptoms of bipolar disorders</title>
            <author>Gudisa Bereda</author>
            <pubDate>2022-04-06 14:14:54</pubDate>
            <description>Bipolar disorder (formerly called manic-depressive illness or manic depression) is a mental disorder that causes unusual shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks. During mood swings, there may be features of psychosis (delusions and hallucinations) that are mood-congruent. Although psychotic symptoms are seen only in a minority of patients, they explain the early terminology of manic&amp;ndash;depressive psychosis. Stage 1a is defined as mild or non-specific symptoms of mood disorder and intervened as formal mental health literacy; family psychoeducation; substance abuse reduction; cognitive behavioral therapy. Euphoric means the experience of pleasure or excitement and intense feelings of well-being and happiness. Certain natural rewards and social activities, such as aerobic exercise, laughter, listening to or making music, and dancing, can induce a state of euphoria. Racing thoughts are consistent, persistent, often intrusive thoughts that come in rapid succession. There is a direct link between depression and anxiety and racing thoughts. Whereas jumping from topic to topic as in the flight of ideas can be observed by others, ascertainment of racing thoughts requires asking the child whether his or her thoughts seem to be going too fast.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1030.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Prevalence of and institutional factors associated with depression among undergraduate students at Gulu University</title>
            <author>Lucas Goodgame Anyayo,Amir Kabunga,Ponsiano Okalo,Brenda Apili,Viola Nalwoga</author>
            <pubDate>2022-03-11 00:00:00</pubDate>
            <description>Background: Many institutional factors predispose University students to mental health issues, including depression. However, with no central database for depression in Uganda, literature on depression and associated institutional factors among undergraduate students is scarce. This study examined the prevalence of and institutional factors associated with depression among undergraduate students at Gulu University.Methods: This was a cross-sectional survey among 452 undergraduate students at Gulu University in the academic year 2018/2019 in February and March 2019. A stratified simple random sampling was used to identify the participants. A self-administered questionnaire was used to collect data. Descriptive statistics, including mean and frequency, were used. We conducted a bivariate analysis to determine the association between variables employing Pearson&amp;rsquo;s chi-square test or Fischer&amp;rsquo;s exact test. We conducted a multivariate analysis with factors that had significant P-values of less than 0.05.Results: The average age of the respondents was 22.4 (SD - 2.4), more than half (53.1%) were male and 38.50% were in the second year. The results show that 31.19% reported depression. After controlling for age and sex, the results showed that there was a statistically significant correlation between depression and faculty (aOR - 1.15), year of study (aOR - 0.77), happiness with the course (aOR - 0-0.49), satisfaction with academic performance (aOR - 0.45), and satisfaction with academic quality (aOR - 0.61). The results indicated that the predictors of depression among undergraduate students were faculty, year of study, satisfaction with academic performance, and satisfaction with academic quality.&amp;nbsp;Conclusion: A substantial proportion of Gulu University undergraduate students reported high levels of depression. The results, therefore, showed that depression in undergraduate students is an identifiable disorder that needs diagnosis, prevention, and treatment. Faculty, year of study, satisfaction with academic performance, satisfaction with academic quality were predictors of depression. Thus there is an urgent need for counseling, psychoeducation, and preventive mental health services as an essential part of the university setup.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1029.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Depression and anxiety during pandemic school shutdowns in post&#45;communist Rural Romania</title>
            <author>Michael J Schöll</author>
            <pubDate>2021-12-17 00:00:00</pubDate>
            <description>&amp;ldquo;Class is part of the meaninglessness of reality,&amp;rdquo; says Lacan. An abundance of narratives concerning post-communist Romanian camps may be found.In a sense, Derrida&amp;rsquo;s essay on education suggests that the goal of the artist&amp;rsquo;s social comment, given that art is interchangeable with a lack of joy. The characteristic theme of educator&amp;rsquo;s model of roles camp is a self-sufficient reality, leading to depression and anxiety.But the subject is contextualized into a cultural Marxism that includes art as a whole. Popescu examines the teacher&amp;rsquo;s camp; in The Crying of Lot, however, he denies the education system&amp;rsquo;s fault.In this article, we determine the factors, leading to depression and anxiety during the current shutdown of schools in permanenting constructional underestimation of teacher&amp;acute;s formation. Maybe, the current situation is better in the way it was than it was. The future will tell.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1028.pdf</link>
        </item> 
                    <item>
            <type>Brief Communication</type>
            <title>Observation of telepsychiatry service in a teaching hospital of eastern Nepal during COVID&#45;19 pandemic</title>
            <author>Dhana Ratna Shakya</author>
            <pubDate>2021-10-14 00:00:00</pubDate>
            <description>Considering the geographical complexity and adversity, online communication and consultation are viable method in Nepal. The COVID-19 pandemic has accelerated the already starting trend of use of these technologies in medicine. In BPKIHS, telemedicine efforts were already initiated; lockdown rather warranted its maximum use. Here is an account of the observation made in telepsychiatry service provided by a consultant psychiatrist of its department of psychiatry. It is an institute-based observation noted for all the telepsychiatry consultations in 9 random duty days of the COVID-19 pandemic. Basic necessary information was noted down in a semi-structured proforma, like: socio-demographic, clinical information and advice provided.&amp;nbsp;There were 104 subjects; 73 follow-up and 31 new: 60 male and 44 female cases. Clients of multi-ethnic groups were the most from urban, then semi-urban and least from rural areas. More consultations were for young age-groups and from nearby districts of Sunsari. Mood, somatic (sleep), anxiety were the top presenting complaints and 8/104 clients had suicidal symptoms. Maximum follow-up cases were improving. The most common diagnoses were: Mood (Depression and Bipolar), Anxiety, Psychosis and Substance use disorders. Most common treatment advices included: Antidepressants, Antipsychotics, Benzodiazepines and Counseling/psycho-education. Telepsychiatry is a viable method of delivering service even during the pandemic.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1027.pdf</link>
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                    <item>
            <type>Research Article</type>
            <title>Depression and anxiety in patients with suspected renal artery stenosis</title>
            <author>Ludvig Hallberg,Anders Gottsater,Anders Isaksson,Asa Westrin</author>
            <pubDate>2021-09-06 00:00:00</pubDate>
            <description>Objective: To investigate the occurrence of depressive and anxiety disorders in patients remitted for endovascular treatment of renal artery stenosis (RAS), and whether symptoms of depression and anxiety can be reduced after the treatment of RAS with percutaneous transluminal renal angioplasty (PTRA).Methods Patients: Selected for renal angiography with pressure measurement in the renal arteries due to suspected RAS were invited to participate in the study. 37 patients agreed to answer a questionnaire. Eighteen patients also agreed to a clinical psychiatric examination including the International Neuropsychiatric Interview (M.I.N.I. 6.0) to be diagnosed according to the DSM-IV.&amp;nbsp;Results: Twenty-one of the 37 patients completing the questionnaire were found to have a pressure gradient of &amp;ge; 10 mmHg at angiography, indicating significant stenosis. Ten of the 18 examined patients met the criteria for current DSM-IV anxiety diagnosis and two patients had a current depression. Three of the 18 examined patients had previously made a suicide attempt.&amp;nbsp;Conclusion: The results of this study suggest that patients with suspected RAS have a high psychiatric comorbidity, as 56% of the patients undergoing psychiatric examination met the DSM-IV criteria for a current anxiety disorder.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1026.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Impact of amitriptyline on learning and memory</title>
            <author>Mfem CC,Seriki SA</author>
            <pubDate>2021-04-14 00:00:00</pubDate>
            <description>Background/aim: Amitriptyline belongs to class of known as tricycline antidepresant (TCA) that is being used to treat anxiety and depressive states. It may help improve mood and feelings of well-being, relieve anxiety and tension, help to improve sleep and increase energy level. The study investigated the effect of amitriptyline on learning and memory using eighteen (18) healthy Swiss mice of both sexes weighing 16 &amp;ndash; 25 g.
Method: The animals were divided into three (3) groups consisting of six (6) animals each. Group 1 served as the control group, Group 2 was administered with amitriptyline at a dose of 3 mg/kg body weight dissolved in 3 mls of distilled water, and used to test for learning, while Group three was also given similar administration like Group 2, but used to test for memory. All the animals were tested for learning and memory performance using Novel object recognition task and Morris water maze test.
Results: The results obtained from the Novel object recognition task showed that there was a significant decrease (p &amp;lt; 0.05) in total object approach in acquisition trial of amitriptyline treated group when compared to the acquisition trial of the control group. There was a significant decrease (p &amp;lt; 0.05) in retention trial of amitriptyline group when compared to retention trial in the control group. There was a significant decrease (p &amp;lt; 0.05) in total duration exploring objects in acquisition trial of amitriptyline treated group when compared to the acquisition trial of the control group. There was a significant increase (p &amp;lt; 0.05) in total duration exploring objects in retention trial of amitriptyline treated group when compared to the retention trial of the control group. There was a significant decrease (p &amp;lt; 0.05) in the index of habituation of amitriptyline treated group when compared to the control group. The index of discrimination showed a significant increase (p &amp;lt; 0.05) in amitriptyline treated group when compared to the control group and a significant decrease (p &amp;lt; 0.05) in amitriptyline group when compared to the control group. In the Morris water maze test, Day 1 &amp;ndash; 3 were for acquisition training, day 4 &amp;ndash; 6 reversal training, day 7 the probe trial day and day 8 the visible platform day. During acquisition training in the Morris water maze test, there was no significant difference in Swim latencies in day 1 and 2. However in day 3, there was a significant increase (p &amp;lt; 0.05) in swim latency of group compared to control group and a significant decrease (p &amp;lt; 0.05) in swim latency of amitriptyline treated group compared to the control group. During reversal training in day 1, 2 and 3, there was no significant difference in swim latency among the three groups. Results for the retention quadrant in the probe trials showed a significant decrease (p &amp;lt; 0.01) in amitriptyline group when compared to the control group.
Conclusion: Results suggest that amitriptyline impairs learning and memory functions.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1025.pdf</link>
        </item> 
                    <item>
            <type>Short Communication</type>
            <title>Burden and depressive symptoms in health care residents at COVID&#45;19: A preliminary report</title>
            <author>Daniela Betinassi Parro-Pires,Sérgio Henrique de C Matias Barros,Fernanda Sabina HD Araújo,Daniel Zandoná Santos,Luiz Antônio Nogueira-Martins,Vanessa de Albuquerque Citero</author>
            <pubDate>2021-04-08 00:00:00</pubDate>
            <description>This paper focuses on the mental health burden on medical and healthcare residents during the 1st wave of COVID-19 pandemic crisis in 2020 describing the activities of a mental health service for residents (NAPREME) in a public university, UNIFESP, Sao Paulo, Brazil; and a preliminary study showing an increasing of depressive symptoms and depression among residents. Data is related to the screening interviews of medical residents and healthcare multi-professional residents who sought the mental health service from March to December 2020. A comparison was conducted with the same period in 2019 (covering a period when Covid-19 was not affecting the Brazilian population). There was a 22% demand increase in 2020. Of the total amount who sought treatment: 23% were medical residents, 22% nursing residents, and the remaining distributed among other professions; and 58% were first year residents and 34% second year. Data from the BDI questionnaire showed some variance between the two years: the mean score for 2020 was 24.67 (&amp;plusmn; 7.86) which is in the depression range, higher than the mean score of 19.91 points in the previous year (&amp;plusmn; 10.15) which is only in the depressive symptoms range (p &amp;lt; 0.005). In the pandemic period there was an increase in residents with depression from 49% to 70%. Depression, anxiety, stress and burnout syndrome were observed, demanding psychological and psychiatric care for this population. Assessment of residents&amp;rsquo; mental health will continue during 2021, during the 2nd wave of COVID-19 and an additional analysis will be conducted along the year.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1024.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Suicidal behaviors as a risk factor among heroin addicts with comorbid depression: A comparative study</title>
            <author>Nazia Mustafa,Fahad Haleem </author>
            <pubDate>2021-01-19 00:00:00</pubDate>
            <description>The main purpose of the present study was to find out the differences on suicidal ideation, hostility, hopelessness and negative self-evaluation among heroin addicts with comorbid depression. After reviewing the literature, it was hypothesized that heroin addicts with high depression may have high scores on variable of suicidal ideation, hostility, hopelessness, and negative self-evaluation as compared to those with low depression. The sample was consisted of 60 males from Low-socioeconomic status (SES) (34 of them were screened as having high scores on the variable of depression and 26 were screened as low scorers). Siddiqui Shah Depression Scale (Siddiqui &amp;amp; Shah, 1997) and Urdu version of Suicide Probability Scale (Cull &amp;amp; Gill, 1982) was administered. To compare heroin addicts with high and low depression on various variables, t - test was applied. The research findings showed that heroin addicts with mean age of 30 years (range 20 to 40) having the mean duration of heroin dependence of 10 years with high depression were significantly high on the variable of suicidal ideation, hostility and hopelessness ((p &amp;lt; .05) as compared to those with low depression. And there was no significant difference on the variable of negative self-evaluation for both groups (p &amp;gt; .05). So it was concluded that services for patients with Heroin addiction should include periodic screening for suicidal behavior along with psychiatric treatment and psychosocial support.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1023.pdf</link>
        </item> 
                    <item>
            <type>Mini Review</type>
            <title>Hormones and depression in women</title>
            <author>John Studd</author>
            <pubDate>2020-10-15 00:00:00</pubDate>
            <description>It is well known that depression is more common in women than in men with more prescriptions for antidepressants, hospital admissions for depression and suicide attempts. However another aspect to be considered is that depression is different in women than men because women have depressive episodes at times of hormonal shift which is a physiological phenomenon not encountered in men. This is why hormone therapy is so important.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1022.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Prevalence and measurement of anxiety and depression in nurses during COVID pandemic in Nepal</title>
            <author>Ayush Chandra,Avinash Chandra,Nabina Sharma</author>
            <pubDate>2020-09-28 00:00:00</pubDate>
            <description>Background: Anxiety and depression are under reported, underdiagnosed mental illness in health worker in Nepal especially during COVID pandemic. The study was carried out as an observational study on nurses in Nepal. In this study we attempted to assess the incidence and impact of depression and anxiety in nurses who are working upfront in different hospitals during this crisis.
Objective: The purpose of the study is to assess the prevalence of anxiety and depression among nurses in Nepal during COVID pandemic who are working in various hospitals.
Method: A cross-sectional non-probability purposive sampling with observational analysis was carried out and the sample was collected from nurses working in different hospitals. Prevalence of anxiety and depression was assessed using a structured and validated questionnaire. Anxiety was assessed with the Hamilton Anxiety Scale (HAM-A), General Anxiety Disorder Questionnaires (GAD) with a cut-off score for various levels of anxiety while Hamilton Depression Rating Scale (HAM-D) was used to assess depression.
Result: The analysis of these different scales revealed that disabling anxiety prevailed at highest (43.6%) in nursing staff according to HAM-A scale. Moderate anxiety also seemed to be higher (&amp;gt; 20%) in GAD questionnaire.
Conclusion: This is the first study carried out in Nepal that investigates the mental health of nurses who are working in the frontline in this COVID pandemic situation. The study revealed that our nurses who have given their life in the line are suffering from serious mental health problems.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1021.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>The relationship of cell phone use and aggression among young adults with moderating roles of gender and marital status</title>
            <author>Asma Naseer,Waqar Husain</author>
            <pubDate>2020-08-26 00:00:00</pubDate>
            <description>The use of cell phones has remarkably increased in the last two decades with several pros and cons. The negative consequences of cell phones on mental health have not been studied widely. Aggression, in this regard was a completely neglected area. The present study, therefore, was carried out to investigate the relationship between cell phone use and aggression and to further identify the moderating roles of gender and marital status between cell phone use and aggression. The inquiry included 500 young adults from Rawalpindi, Pakistan. Buss and Perry Aggression Questionnaire was administered. It was hypothesized that there would be a strong positive relationship between cell phone use and aggression. It was further hypothesized that gender and marital status would be significant moderators between cell phone use and aggression. The results supported the hypotheses on significant differences and made a significant contribution in the existing scientific literature.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1020.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Psychological studies of stress experienced by seamen during a long&#45;distance sea voyage#</title>
            <author>Mieczysław Plopa</author>
            <pubDate>2020-08-25 00:00:00</pubDate>
            <description>The issues investigated in the current study pertain to selected psychological aspects of human functioning in long-term stress conditions. Results of the analyses performed in this study have submitted evidence to confirm the hypothesis in which it is stated that staying on the sea for a long time is a difficult situation which contributes - to a greater or smaller extent - to starting the stress process in sailors. The role of interpersonal competencies that has been found most distinct; high level of this variable contributed to reducing both anxiety and the feeling of loneliness. It has been evidenced in the research that the skill of good functioning in varied social groups, which results from high level of development of several traits including: openness, spontaneity, responsibility, and sensitivity, becomes particularly important in long-term difficult situations in which there is little possibility of eliminating the real menace.
Another conclusion to be inferred from the research is the one confirming the theoretical suggestion in which the importance of &amp;lsquo;ego strength&amp;rsquo; in modifying the course of stress process is emphasised. This personality dimension has turned out to constitute the factor capable of protecting an individual against increase in both anxiety states and the feeling of loneliness during sea isolation.
Another issue considered in the current study pertains to defining the role of &amp;lsquo;family variable&amp;rsquo; in mediating the course of stress process under conditions of long-term task isolation. The analyses have confirmed the hypothesis in which it was assumed that sailors functioning in family systems characterised by high level of integration and quality, experience lower emotional costs during a voyage. Generally, it may be claimed that - according to the research results of the study - &amp;lsquo;family variables&amp;rsquo; may constitute a significant predictor of both the &amp;lsquo;quality&amp;rsquo; of a man&amp;rsquo;s functioning and personal costs he experiences in long-term stress conditions.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1019.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Socio&#45;demographic characteristics and other factors associated with depressive illness among medical students at the University of Port Harcourt</title>
            <author>Asuquo EO,Nkporbu AK,Okechukwu C,Onoh I,Okafor NT</author>
            <pubDate>2020-05-14 00:00:00</pubDate>
            <description>Background: The burden of depression as a mental disorder has continued to increase and constituting an enormous public health concern among all age groups. A number of socio-demographic, and other factors including a stressful and rigorous academic programme or curriculum such as the one run in most medical schools could contribute to the occurrence of depression among medical students.
AIM: To determine the socio-demographic and other factors associated with depression among medical students in the University of Port Harcourt.
Methodology: This study was a descriptive cross-sectional study. Appropriate sample size was calculated and the stratified random sampling method was used to select the subjects. A well-structured open ended self-administered socio-demographic questionnaire was administered to the students. The Zung Self-Rated Depression Scale was used to assess the depression status of each respondent. The data were analyzed via descriptive and analytical methods.
Results: The prevalence of depression among the medical students was 5.3%. Fourteen students (4.6%) were mildly depressed while only two respondents had moderate depression. Year 3 had the highest prevalence with 10.5% followed by final year with 5.3%, while the only 2 cases of moderate depression were found among students in year 2 of their medical programme. Two hundred and seventy-one respondents (88.8%) were found to have good knowledge of depression, 32 (10.5%) were found to have average knowledge of depression and 2(0.7%) had poor knowledge of depression.
Conclusion: Depression does occur among medical students at the University of Port Harcourt albeit low, and was associated with a number of socio-demographic and other factors. The present medical curriculum and programme should be sustained and more efforts at making it less stressful and academically friendly, be made to further reduce the current rate of psychological stress and depression among the students.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1018.pdf</link>
        </item> 
                    <item>
            <type>Brief Communication</type>
            <title>Problems shared in psychiatry helpline of a teaching hospital in eastern Nepal during COVID&#45;19 pandemic lockdown</title>
            <author>Dhana Ratna Shakya</author>
            <pubDate>2020-04-27 00:00:00</pubDate>
            <description>COVID-19 pandemic soon apparently proved to be havoc and a great stressor. During such a stressful time, mental health is in threat. Here, we intend to review the presenting problems/ symptoms as shared in psychiatry helpline of a Teaching Hospital in eastern Nepal during the second week of lockdown and to reflect on to emotional, including mood problems.
It is an institute based period observation noted for all psychiatry helpline calls during 1 week of lockdown days of COVID-19. Their concerns and problems were listened and symptoms clarified by a consultant psychiatrist to help them as far as possible through the telephonic conversation. Maintaining the confidentiality, basic information were noted down in a semi-structured proforma to record certain socio-demographic and clinical information (including mood and other emotional symptoms).
We received 102 helpline calls of 60 clients for psychiatry in 1 week, from 14 districts. More patients being discussed were males (35/60), average age being 34.15 (15 - 70) years. More patients were regular follow-up cases with some new issues (24/60) and 18/60 each were new clients and regular follow-up cases. Majority had exacerbated symptoms in the wake of COVID-19 as: emotional (47/60; mood 24/60, anxiety/worry 23/60) symptoms along with disturbed sleep (32/60); treatment/service issues (31/60) and changed routines. Most common mental problems were Bipolar affective disorder, Psychosis, Anxiety and Depression and advices included Antipsychotics, Benzodiazepines, Antidepressants, along with some Psycho-education. Most common concerns were about OPD service, worsening symptoms and local unavailability of medicines. Many had mood and emotional symptoms in this stressful time, both simple amenable to telephonic advices and severe requiring to be called to emergency service.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1017.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Therapeutic application of herbal essential oil and its bioactive compounds as complementary and alternative medicine in cardiovascular&#45;associated diseases</title>
            <author>Ahmad Firdaus B Lajis,Noor Hanis Ismail</author>
            <pubDate>2020-03-10 00:00:00</pubDate>
            <description>Background: Herbal essential oil contains pharmacological benefits for intervention treatment of various diseases. Studies have demonstrated its antimicrobial, antioxidant, and anti-inflammatory effect involving in vitro cell culture and preclinical animal models. It has been also traditionally used to reduce anxiety and hypertension in human. However, scientific studies elucidating its mechanism of action and pharmacological targets, as well as its effectiveness and safety as phytotherapeutic compounds are still progressing. Recent studies showed its promising effect in depression-cardiovascular disease intervention. However, comprehensive evaluations to enlighten latest advancement and potential of herbal essential oil are still lacking.
Objective: In this systematic review, the depression-cardiovascular effects of herbal essential oil on lipid profile, biochemical and physiological parameters (e.g haemodynamic) are presented. The route of delivery and mechanism of action as well as main bioactive compounds present in respective essential oil are discussed.
Methods: Article searches are made using NCBI PubMed, PubMed Health, SCOPUS, Wiley Online, tandfonline, ScienceDirect and Espacenet for relevant studies and intellectual properties related to essential oil, depression and cardiovascular disease.
Results: In experimentation involving in vitro, in vivo and clinical trials, herbal essential oil showed its effectiveness in reducing coronary artery disease (narrowing of the arteries), heart attack, abnormal heart rhythms, or arrhythmias, heart failure, heart valve disease, congenital heart disease, heart muscle disease (cardiomyopathy), pericardial disease, aorta disease, Marfan syndrome and vascular (blood vessel) disease.
Conclusion: This review gives a valuable insight on the potential of essential oil in the intervention of depression associated with cardiovascular diseases. Studies showed that herbal essential oil could act as vasodepressor, calcium channel blocker, antihyperlipidemia, anticoagulant, antiatherogenesis and antithrombotic. It can be proposed as an interventional therapy for depression-cardiovascular disease to reduce doses and long-term side-effect of current pharmacological approach.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1016.pdf</link>
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                    <item>
            <type>Research Article</type>
            <title>Impact of Christian meditation and biofeedback on the mental health of graduate students in seminary: A pilot study</title>
            <author>Paul Ratanasiripong,Sun Tsai </author>
            <pubDate>2020-03-09 00:00:00</pubDate>
            <description>With increasing awareness of the mental health issues among the clergy and seminary students, it is important to explore possible interventions to help address their mental health concerns. This pilot study examined the impact of Christian meditation and biofeedback on levels of stress, anxiety, and depression of seminary students. Participants of this study included 20 theology students from two seminary campuses. Participants were of various ethnic backgrounds and had an average age of 31. At the beginning of the study, participants were randomly assigned to practice either Christian meditation or biofeedback for 4 weeks, three times per day, and to keep a log of their practice times. The results from the paired samples t-tests indicated that both Christian meditation and biofeedback significantly reduced the levels of stress, anxiety, and depression experienced by the participants. ANCOVA indicated that neither intervention was more effective than the other. Seminaries, churches, and pastoral care groups should look into these interventions as a good source to help their clergy cope with stress, anxiety and depression.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1015.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>The different levels of depression and anxiety among Pakistani professionals</title>
            <author>Sehrish Hassan,Waqar Husain</author>
            <pubDate>2020-03-05 00:00:00</pubDate>
            <description>The present study was conducted to examine the relationship between work-stress, depression and anxiety among six major professionals (doctors, engineers, bankers, nurses, teachers, and lawyers). The inquiry included 260 professionals from different private and governmental sector organizations of Rawalpindi and Islamabad, Pakistan. Job Stress Scale and the subscales of Depression, Anxiety &amp;amp; Stress Scale for depression and anxiety were administered. Based on the hypotheses, a strong positive correlation was found between work stress and depression &amp;amp; anxiety. The current study revealed that stress at work not only prevailed among different Pakistani professionals on severely alarming levels but significantly contributed in developing depression and anxiety.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1014.pdf</link>
        </item> 
                    <item>
            <type>Mini Review</type>
            <title>Depression as a civilization&#45;deformed adaptation and defence mechanism</title>
            <author>Bohdan Wasilewski,Olha Yourtsenyuk,Eugene Egan</author>
            <pubDate>2020-03-02 00:00:00</pubDate>
            <description>Depression is currently one of the main barriers to further civilizational development. Despite intensive efforts, it is a growing health, social and economic problem. We still lack clarity regarding the ethology of depression and treatment is still mainly symptomatic. The authors postulate that depression has similarities with anxiety and from an evolutionary perspective is an archaic defence mechanism. Formerly, through the agency of complex psychological, biological and social mechanisms, healing was facilitated in conditions of an intense, short-term nature. Adverse civilizational and environmental changes have caused pathological changes in both the mechanism of depression and corresponding defence mechanisms such as the induction of an anxiety state. Related to depression is the mechanism of thanatosis, concerning chronic biological and psychosocial dysfunctions. It is a mechanism for activating self-eliminating processes to free the community from the burden of a dysfunctional individual.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1013.pdf</link>
        </item> 
                    <item>
            <type>Case Report</type>
            <title>Symptomatic cluster&#45;like headache in Normal&#45;Pressure Hydrocephalus (NPH) and possible arteritis: Case report and an overview of the literature on secondary cluster&#45;like headaches</title>
            <author>Stefania Peruzzo,Carlo Lovati</author>
            <pubDate>2020-02-27 00:00:00</pubDate>
            <description>Cluster headache (CH) is a primary headache belonging to the group of trigeminal-autonomic cephalalgias, characterized by short attacks of very severe headache, always involving the same side of the head, more frequently localized to the periorbital and temporal area, associated with homolateral tearing, red eye, nose obstruction or rhinorrhea, ptosis, miosis, and restlessness. These attacks generally last 15-180 minutes and can occur from once every day to 8 times a day.&amp;nbsp;</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1012.pdf</link>
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            <type>Research Article</type>
            <title>Translation, adaptation and validation of Depression, Anxiety and Stress Scale in Urdu</title>
            <author>Waqar Husain,Amir Gulzar</author>
            <pubDate>2020-02-25 00:00:00</pubDate>
            <description>The current study was carried out to translate, adapt and validate Depression, Anxiety and Stress Scale in Urdu language and in Pakistani culture. The current translation was aimed to produce a more user friendly and clinically applied version of DASS. The systematic procedure involved in translation focused on maximizing levels of semantic and conceptual equivalence. A test re-test pilot study was conducted on 30 participants to analyze the translated version initially, the results of which determined a significant positive correlation between original and translated versions. The main study involved 300 conveniently selected Pakistanis. The findings revealed that the translated version titled U-DASS-42 was highly reliable and valid in Pakistani culture. The newly developed U-DASS-42 is attached with this paper for the convenience of Pakistani researchers.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1011.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Sleeplessness and health</title>
            <author>Sunitha V,Jeyastri Kurushev,Felicia Chitra,Manjubala Dash</author>
            <pubDate>2019-04-30 00:00:00</pubDate>
            <description>Sleep influences each intellectual and physical health. It&amp;rsquo;s essential for a person&amp;rsquo;s well-being. The reality is when we see at well-rested people, they&amp;rsquo;re working at an exclusive degree than people making an attempt to get by way of on 1 or 2 hours much less nightly sleep. Loss of sleep impairs your higher tiers of reasoning, problem-solving and interest to detail. Sleep deficit will additionally make people much less productive and put them at higher danger for creating depression. Sleep affects almost each tissue in our bodies. It influences growth and stress hormones, our immune system, appetite, breathing, blood pressure and cardiovascular health. Nurses play a foremost function in teaching and guiding the sleep deprived patients on the importance of sleep and its physiological and psychological effects.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1010.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Anti&#45;anxiety effects in mice following acute administration of Ficus Thonningii (wild fig)</title>
            <author>Aduema W,Akunneh-Wariso C,Ejiofo DC,Amah AK</author>
            <pubDate>2018-09-11 00:00:00</pubDate>
            <description>The effect of acute administration of ethanol extract of F. thoningii on anxiety and fear in Swiss white mice was studied. 30 adult Swiss white mice of both sexes were randomly divided in to three groups of 10 mice each. Group1 served as the control and was administered normal saline only. Group 2 (low dose group) was administered 10mg/kg ethanol extract of the F. thoningii, while group 3 (high dose group) was given 20mg/kg of the same extract. All animals were allowed food and water ad libitum. Neurobehavioral parameter was assessed using the light/dark transition box. The analysis of variance (ANOVA) was used to test for variability within and among groups. Results were expressed as Mean &amp;plusmn;SEM (standard error of the mean) and probability level p&amp;lt;0.05 was accepted as significant. The result showed that the frequency of transition in the light/dark transition box was significantly increased in the test groups (p&amp;lt;0.05; p&amp;lt;0.01).Similarly, the Light Box Duration was also significantly increased (p&amp;lt;0.01) in the low and high dose groups respectively. However, the Dark box duration was significantly decreased (p&amp;lt;0.05; p&amp;lt;0.01) in the low and high dose groups compared to control. This index showed a decreased level of anxiety and fear in the test groups. This was followed by a corresponding trend of decreased frequency of stretch attend posture and duration of freezing in the light/dark transition box (p&amp;lt;0.01; p&amp;lt;0.001) compared to the control. Summarily, acute administration of ethanol extract of F. thonningii causes calmness and sedation in moderate and high doses. It is therefore likely that it reduces aggression. If the result from this finding is extrapolated to humans, F. thoningii could be used to reduce anxiety disorders.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1009.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Mindset kinetics and some depression status: A new quantitative model under biochemical &#45; toxicology approach?</title>
            <author>Luisetto M,Ghulam Rasool Mashori,Behzad Nili-Ahmadabadi,Farhan Ahmad Khan,Kausar Rehman Khan</author>
            <pubDate>2018-07-24 00:00:00</pubDate>
            <description>Depression: According Pubmed Health: Depression is a state of low mood and aversion to activity that can affect a person&amp;rsquo;s thoughts, behavior, feelings and sense of well-being (moderate or severe).
Can we consider some depression status due to high amount of some stressant stimulus? Or continuous stress in a limited (or long) period? How can react mindset and brain in management an high amount of negative stressing thinking? Observing some relevant literature also mindset kinetics must be considered to better classify this kind of disorder under a specific endogenous &amp;ndash;exogenous biochemical-toxicological aspect.
Concept like Kinetics, reaction velocity limits, saturation of the systems, residual buffer properties are currently used in biochemistry and related discipline.
This concepts can be applied also in some depression condition to better explain some phenomena?</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1008.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Responding to Disasters: More than economic and infrastructure interventions</title>
            <author>David Crompton OAM,Ross Young,Jane Shakespeare-Finch,Beverley Raphael AM</author>
            <pubDate>2018-04-24 00:00:00</pubDate>
            <description>Objectives: Natural disasters confront individuals, communities and governments with the challenge of rebuilding and addressing psychosocial sequelae. With the increasing number of natural disasters it is timely to evaluate the efficacy of interventions and strategies to address the mental health needs of individuals and the community.
Method: An evaluation of literature related to the psychological impact of natural disasters, treatment efficacy and government strategies to confront the social and psychological impact of natural disasters for the period 1983-2016 was undertaken.
Results: Epidemiological studies following natural disasters despite the use of differing psychological measures demonstrate significant psychological morbidity - anxiety (7-42%), complicated grief (28-41%), depression (6.5-38%), post-traumatic stress disorder (11-89%) and substance misuse (1.3-24%). Intervention studies post-disaster demonstrate efficacy variability.
Conclusions: The increase in the number and impact of meteorological and hydrological events since the 1980s and the psychological, social and economic consequences of these events has resulted in the development and implementation of government policies to confront the immediate and long-term adverse outcomes. The focus is typically on resources and infrastructure redevelopment with less focus on social and mental health interventions with long-term evaluation of interventions uncommon. The consequence of natural disasters emphasizes the importance developing strategies to ensure effective evaluated psychosocial interventions are available across at-risk communities.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1007.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Vestibular&#45;limbic relationships: Brain mapping</title>
            <author>Paolo Gamba</author>
            <pubDate>2018-03-16 00:00:00</pubDate>
            <description>Vestibular disorders and anxiety are closely related, probably because they share some neuronal pathways. Ageing and patient comorbidities are important facilitating factors, and multiple vascular risk factors could contribute to the onset of a vestibular syndrome called vascular vertigo. White matter lesions (WML) are often seen on magnetic resonance imaging (MRI) scans of elderly people and are related to various geriatric disorders, including dizziness. The cause of this correlation could be the disruption of neuronal networks that mediate higher vestibular cortical function. Numerous neuronal pathways link the vestibular network with limbic structures and the prefrontal cortex modulates anxiety through its connections to amygdala. The aim of the present work was to investigate the correlation between WML, amygdala and cognitive functions.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1006.pdf</link>
        </item> 
                    <item>
            <type>Case Report</type>
            <title>May we feed cancer?</title>
            <author>Maria Grazia Spurio</author>
            <pubDate>2018-02-12 00:00:00</pubDate>
            <description>The patient with an oncological disease presents a series of discomforts related to the psychological sphere such as depression, pain, sense of usefulness, anger, but also inconveniences related to food sphere. Neoplastic disease interferes with eating behaviour for several reasons. The communication of the diagnosis can create a state of anorexia as a result of the shock; certain tumours of the gastrointestinal tract-gold (mouth, esophagus, stomach, colon and rectum, but also pancreas and liver) are directly responsible for the possible alteration of food intake; alteration in eating behaviour may be secondary to the main therapeutic treatments. The link between food and cancer is not only evident in case of disease, but also in case of prevention, in fact a growing number of studies indicates more an more clearly the close correlation between a healthy diet and prevention of oncological diseases although at present time it is not still possible to give definitive results. The diagnosis of a person is like a melody in which some notes are repeated but their combination is almost infinite, because each person has different eating needs, as well as different psychological needs, and the starting point for a good professional must necessarily be a &amp;lsquo;customized&amp;rsquo; diagnosis. This &amp;lsquo;diagnosis of well-being&amp;rsquo;, tailor-made for each person, involves professionals in both the food and psychological and behavioural sectors, since the individual needs have to be evaluated globally.
Finally, the professionals of human behaviour in food consumption, and the chemical and science processing experts, have the duty not to limit themselves to a single refusal against the use of certain foods, but framing the phenomenon in a wider perspective and, as experts of human health, to propose alternatives.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1005.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Spiritual and religious Islamic perspectives of healing of posttraumatic stress disorder</title>
            <author>Mevludin Hasanović,Izet Pajević,Osman Sinanović</author>
            <pubDate>2017-09-25 00:00:00</pubDate>
            <description>It is known today that psycho-trauma and PTSD cause different levels of mental and social dysfunction. Human spirituality and capacity to meet further life difficulties become severely damaged. There is wide accepted attitude today that in holistic approach in process of healing PTSD and psycho-trauma is necessary to include other professionals from community resource regarding needs of trauma victims. In Bosnia and Herzegovina after very severe war (1992-1995) as mental health professionals, we are faced with increasing number of different mental health disorders as result of severe trauma experiences. Regarding community based care orientation it is necessary to include and religion professionals. According national and religious background of majority of our population in Tuzla Canton that is Muslim, we meet spiritual needs of our clients as needs for Islamic explanation of life and death meaning. Our clients need to talk about spiritual issues in daily therapy and to practice daily religious rituals. Regarding that in this paper we tried to interface Islamic principles and it&amp;rsquo;s beneficial toward psycho-trauma and PTSD, as well as Muslim perspectives in attempt to apply spiritual practice in therapeutic tools for better efficacy in spiritual healing of mental dysfunction&amp;rsquo;s of believers who survived severe trauma, especially war trauma.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1004.pdf</link>
        </item> 
                    <item>
            <type>Review Article</type>
            <title>Anxiety and depression as an effect of birth order or being an only child: Results of an internet survey in Poland and Germany</title>
            <author>Jochen Hardt,Lisa Weyer,Malgorzata Dragan,Wilfried Laubach</author>
            <pubDate>2017-09-14 00:00:00</pubDate>
            <description>Background: Various studies examined the effect of birth order. First born children show usually better cognitive performance than their later born siblings. Studies on emotional aspects yield heterogeneous results, sometimes in favour of first born, sometimes in favour of later born children. Studies comparing only-children with children with siblings are rare.
Method: An internet survey was performed in 508 Polish and 500 German subjects. Only-children, first born, middle born and latest born children were compared regarding body mass index, depression, anxiety and partnership.
Results: No differences among first born, middle born and latest born children were detected. Only-children reported significantly less symptoms of social phobia than first born children (z=0.50, p&amp;lt; 0.01).
Conclusions: Except for suicidality, the results of this study question the sense of further investment in studying effects of birth order. In contrast, examining differences between only-children vs. children having siblings seems to have the potential to yield interesting and new results. Optimally, such research would combine self-report measures with reports from others, such as parents, teachers or clinicians.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1003.pdf</link>
        </item> 
                    <item>
            <type>Mini Review</type>
            <title>Multi&#45;factorial Depressive Disorders Need Multi&#45;dimensional Interventions</title>
            <author>Mustafa Melih Bilgi</author>
            <pubDate>2017-05-04 00:00:00</pubDate>
            <description>Depressive disorders are so frequent and disabling health conditions which have been inarguably accepted to be a public health concern [1]. Many drugs have been developed to treat depression, however the efficacy of the antidepressants are inadequate particularly for mild or moderate depression [2-4]. It is also mentioned that when considering the trials about the treatment effect of the antidepressants, you should be careful about the results because of reflecting a small proportion of the society [4]. Despite the methodological issues related to the controversial results about the antidepressant efficacy, a recent review showed that the antidepressant effects of the drugs persist in a six month period [5,6].</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1002.pdf</link>
        </item> 
                    <item>
            <type>Research Article</type>
            <title>Burnout and Related Factors in Caregivers of outpatients with Schizophrenia</title>
            <author>Hatice Demirbas,Erguvan Tugba Ozel Kizil</author>
            <pubDate>2017-03-09 00:00:00</pubDate>
            <description>Objectives: Care of a person with schizophrenia involves multiple problems, possibly leading to burnout which is a culturally influenced phenomenon. The aim of this study was to investigate burnout and related factors in caregivers of outpatients with schizophrenia.
Methods: Subjects included in the study were 40 primary caregivers of outpatients with schizophrenia (15 males, 25 females) whom were assessed with the Maslach Burnout Inventory (MBI), the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI). Patients were also administered the Calgary Depression Scale (CDS). Also, sociodemographic information about patients and their caregivers were taken. The significance of differences between two groups was determined by Mann-Whitney U-test. The relationships between the variables were evaluated by Pearson correlation analysis.
Results: No significant difference was found in the MBI subscale scores in terms of caregivers gender, marital status, and education, being a family member, having enough information about the illness and taking support during caregiving. Emotional Exhaustion and Personal Accomplishment subscale scores of the caregivers were significantly different in terms of patients&amp;rsquo; adaptation to treatment or not (respectively; p=0.010, p=0.030). The MBI-Emotional Exhaustion scores revealed significant positive correlations with the BDI and BAI total scores. Also, the MBI- Depersonalization scores and the BAI scores were positively correlated.
Conclusions: Burnout levels in caregivers of patients with schizophrenia were lower when compared with other cultures. Only treatment compliance predicted burnout, while other factors were excluded. Therefore, professionals have to help to patients primarily adapt to their treatment.</description>
            <link>https://www.depanxietyjournal.com/articles/ida-aid1001.pdf</link>
        </item> 
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